The role of red yeast rice (RYR) supplementation in plasma cholesterol control: A review and expert opinion.
(2019) Atherosclerosis. Supplement — Vol. 39, p. e1-e8 (2019)
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- 1. Preamble : Hypercholesterolemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD) [1]. Increased levels of low density lipoprotein cholesterol (LDL-C) are associated with an increased risk of coronary heart disease (CHD) and many clinical trials have shown that reducing LDL-C levels significantly reduced the CHD and CVD risk [[2], [3], [4], [5]]. Thus LDL-C-lowering is the main approach for the management of cardiovascular disease. Current guidelines suggest LDL-C levels targets based on the individual CV risk; such targets can be achieved by several means, which include both lifestyle changes and pharmacological approaches [6], with statins being the cornerstone of cardiovascular prevention. [...]
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Banach, M., Bruckert, E., Descamps, O., Ellegård, L., Ezhov, M., Föger, B., Fras, Z., Kovanen, P. T., Latkovskis, G., März, W., Panagiotakos, D. B., Paragh, G., Pella, D., Pirillo, A., Poli, A., Reiner, Ž., Silbernagel, G., Viigimaa, M., Vrablík, M., & Catapano, A. L. (2019). The role of red yeast rice (RYR) supplementation in plasma cholesterol control: A review and expert opinion. Atherosclerosis. Supplement, 39, e1-e8. https://doi.org/10.1016/j.atherosclerosissup.2019.08.023 (Original work published 2019)