Atopic dermatitis : disease management in the era of new systemic immunomodulatory therapies
(2026)
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- Authors
- Supervisors
- Baeck, Marie
- Abstract
- Atopic dermatitis is the most common chronic inflammatory skin disease. Characterized by eczema and intense itch, it profoundly impairs patients’ quality of life. This thesis explores three complementary approaches to improve the management of severe forms: real-world evaluation of new systemic immunomodulatory treatments, validation of a dynamic patient-reported score (Atopic Dermatitis Activity Score 7 - ADAS7) to better capture disease activity, and molecular profiling to distinguish eczema subtypes and better understand therapeutic resistance. The findings confirm the effectiveness and safety of several recent treatments, validate ADAS7 as a practical tool to monitor both severity and disease activity, and highlight specific immunological signatures. Together, these results pave the way for more personalized medicine in atopic dermatitis.
- Affiliations
Citations
De Greef, A. (2026). Atopic dermatitis : disease management in the era of new systemic immunomodulatory therapies. https://hdl.handle.net/2078.5/267247