Modified pig islets for diabetes treatment

Dufrane,Denis;Veriter, Sophie;Gianello, Pierre
(2013)

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Authors
  • Dufrane,DenisUCLouvain
    Inventor
  • Veriter, SophieUCLouvain
    Inventor
  • Gianello, PierreUCLouvain
    Inventor
Abstract
The present invention relates to a modified pig islet capable of producing higher levels of glucagon than a native pig islet or capable of producing a glucagon analog, and methods for obtaining thereof. The invention also relates to a method for treating Diabetes Mellitus, and/or for regulating blood glucose levels in a subject in need thereof, comprising the administration of the modified pig islets of the invention.
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Dufrane, D., Veriter, S., & Gianello, P. (2013). Modified pig islets for diabetes treatment. https://hdl.handle.net/2078.5/26961