Microwave-assisted solvent-free synthesis of hexahydrochromeno-[4,3-b]pyrroles

Pospisil, Jiri;Potacek, Milan
(2004) EUROPEAN JOURNAL OF ORGANIC CHEMISTRY —

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  • Pospisil, JiriMasaryk University
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  • Potacek, MilanMasaryk University
    Author
Abstract
We report the microwave-assisted solvent-free synthesis of hexahydrochromeno[4,3-b]pyrroles. Intramolecular 1,3-dipolar cycloadditions proceed under these conditions within 15 min in 80% yields. Moreover, we have observed pronounced steric requirements of alkyl substituents toward the 1,3-dipolar cycloadditions. (C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.
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Pospisil, J., & Potacek, M. (2004). Microwave-assisted solvent-free synthesis of hexahydrochromeno-[4,3-b]pyrroles. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. https://doi.org/10.1002/ejoc.200300481