Corticosteroid cross-reactivity: clinical and molecular modelling tools.
(2011) Allergy — Vol. 66, n° 10, p. 1367-1374 (2011)
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- Authors
- Abstract
- Two patient profiles with probably different areas of immune recognition are identified as follows: the profile 1 patients were allergic to the frequently positively reacting cluster 1 only, for whom electrostatic fields (molecular charge) seem important; the profile 2 patients reacted to clusters 1 and 2 and/or 3, for whom steric fields (structure) are determinant and who probably presented a global recognition of the corticosteroid skeleton. A modified classification is thus proposed.
- Affiliations
ORL et Dermatologie
Citations
Baeck, M., Chemelle, J. A., Goossens, A., Nicolas, J. F., & Terreux, R. (2011). Corticosteroid cross-reactivity: clinical and molecular modelling tools. Allergy, 66(10), 1367-1374. https://doi.org/10.1111/j.1398-9995.2011.02666.x (Original work published 2011)