Liver Transplantation in Primary Hyperoxaluria Type 1: We Have to Find an Alternative!

Devresse, Arnaud;Godefroid, Nathalie;Anthonissen, Blaise;Labriola, Laura;Kanaan, Nada;et.al.
(2021) Transplantation — Vol. 105, n° 4, p. e46-e47 (2021)

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Abstract
(en) Primary hyperoxaluria type 1 (PH1) is a rare autosomal recessive disease caused by the functional defect of hepatic alanine-glyoxylate aminotransferase (AGT), resulting in the overproduction of oxalate (Figure 1). It leads to early end-stage renal disease (ESRD) in most patients.1 To date, the only way to cure PH1 patients with ESRD is dual liver-kidney transplantation. [...]
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Devresse, A., Godefroid, N., Anthonissen, B., Labriola, L., De Magnée, C., Reding, R., Sokal, E., Stephenne, X., Gillion, V., & Kanaan, N. (2021). Liver Transplantation in Primary Hyperoxaluria Type 1: We Have to Find an Alternative! Transplantation, 105(4), e46-e47. https://doi.org/10.1097/TP.0000000000003597 (Original work published 2021)