Dramatic osteonecrosis of the jaw associated with oral bisphosphonates, periodontitis, and dental implant removal.
(2015) Journal of Clinical Periodontology — Vol. 42, n° 2, p. 190-195 (2015)
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- Abstract
- (en) INTRODUCTION: Osteoporosis affects millions of elderly patients, and anti-resorptive drugs (ARD) such as bisphosphonates (BP) represent the first-line therapy. Despite the benefits related to the use of these medications, osteonecrosis of the jaw is a significant complication in a subset of patients receiving these drugs. CASE PRESENTATION: This report documents a case of dramatic bisphosphonate-related osteonecrosis associated with periodontitis and dental implant removal in an osteoporotic patient treated with per os bisphosphonates for an uninterrupted period of 15 years. CONCLUSION: The aim of this report was to discuss the administration period of BP in the treatment of osteoporosis, the decision-making and clinical management of severe MRONJ and the indications for dental implant placement in these specific patients.
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Fernández Ayora, A., Herion, F., Rompen, E., Reginster, J. Y., Magremanne, M., & Lambert, F. (2015). Dramatic osteonecrosis of the jaw associated with oral bisphosphonates, periodontitis, and dental implant removal. Journal of Clinical Periodontology, 42(2), 190-195. https://doi.org/10.1111/jcpe.12322 (Original work published 2015)