Gene expression profiling in the synovium identifies a predictive signature of absence of response to adalimumab therapy in rheumatoid arthritis.

Badot, Valérie;Galant, Christine;Nzeusseu Toukap, Adrien;Théate, Ivan;Lauwerys, Bernard;et.al.
(2009) Arthritis Research & Therapy — Vol. 11, n° 2, p. R57 (2009)

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Abstract
To identify markers and mechanisms of resistance to adalimumab therapy, we studied global gene expression profiles in synovial tissue specimens obtained from severe rheumatoid arthritis (RA) patients before and after initiation of treatment.
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Badot, V., Galant, C., Nzeusseu Toukap, A., Théate, I., Maudoux, A.-L., Van den Eynde, B., Durez, P., Houssiau, F., & Lauwerys, B. (2009). Gene expression profiling in the synovium identifies a predictive signature of absence of response to adalimumab therapy in rheumatoid arthritis. Arthritis Research & Therapy, 11(2), R57. https://doi.org/10.1186/ar2678 (Original work published 2009)