Preanalytical Conditions Impact Fibrin Monomers but Not D-Dimer: A Study With Rigorous Comparisons of a Broad Range of Simulated Conditions.

Bouarroudj, Hachem Zakaria;Hardy, Michaël;Lecompte, Thomas;Mullier, François
(2025) International Journal of Laboratory Hematology (Print) — Vol. 47, n° 2, p. 330-335 (2025)

Files

BouarroudjHZIntJLabHematol2024.pdf
  • Open Access
  • Adobe PDF
  • 1.86 MB
Download

Details

Authors
Abstract
(en) Dear editors, Fibrin monomers (FMs) and D-dimer are fibrin-related biomarkers of in vivo coagulation activation. Daily monitoring of FMs and D-dimer levels can be useful in the hospital setting for the detection of thrombotic events (TEs) in patients with severe COVID-19 [3, 4]. Indeed, FMs have the advantage of being at normal plasma levels before the occurrence of TEs and of rising suddenly and sharply, specifically capturing fibrin formation. However, FMs levels quickly return to normal (average half-life 2–6 h), resulting in transient plasma peaks. [...]
Affiliations

Citations

  • APA
  • Chicago
  • FWB

Bouarroudj, H. Z., Hardy, M., Lecompte, T., & Mullier, F. (2025). Preanalytical Conditions Impact Fibrin Monomers but Not D-Dimer: A Study With Rigorous Comparisons of a Broad Range of Simulated Conditions. International Journal of Laboratory Hematology (Print), 47(2), 330-335. https://doi.org/10.1111/ijlh.14385 (Original work published 2025)