Profuse oral secretions after propafenone administration in neonates.

Piersigilli, Fiammetta;Auriti, Cinzia;Silvetti, Massimo Stefano;Marrocco, Gabriella;Seganti, Giulio;et.al.
(2010) The Journal of Pediatrics — Vol. 157, n° 5, p. 856-857 (2010)

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Authors
  • Author
  • Auriti, Cinzia
    Author
  • Silvetti, Massimo Stefano
    Author
  • Marrocco, Gabriella
    Author
  • Seganti, Giulio
    Author
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Abstract
Propafenone, an antiarrhythmic drug that is effective for treating supraventricular tachycardias, can induce well-known proarrhythmic and systemic adverse effects. We describe a previously unreported adverse effect in 3 newborns: oral propafenone-induced profuse oral secretions and respiratory distress of sufficient severity to necessitate discontinuation of propafenone.
Affiliations
  • Bambino Gesù Children’s Hospital – (Italy) RomaDepartment of Medical and Surgical Neonatology

Citations

Piersigilli, F., Auriti, C., Silvetti, M. S., Marrocco, G., Drago, F., & Seganti, G. (2010). Profuse oral secretions after propafenone administration in neonates. The Journal of Pediatrics, 157(5), 856-857. https://doi.org/10.1016/j.jpeds.2010.06.028 (Original work published 2010)