Propafenone, an antiarrhythmic drug that is effective for treating supraventricular tachycardias, can induce well-known proarrhythmic and systemic adverse effects. We describe a previously unreported adverse effect in 3 newborns: oral propafenone-induced profuse oral secretions and respiratory distress of sufficient severity to necessitate discontinuation of propafenone.
Affiliations
Bambino Gesù Children’s Hospital – (Italy) RomaDepartment of Medical and Surgical Neonatology
Citations
APA
Chicago
FWB
Piersigilli, F., Auriti, C., Silvetti, M. S., Marrocco, G., Drago, F., & Seganti, G. (2010). Profuse oral secretions after propafenone administration in neonates. The Journal of Pediatrics, 157(5), 856-857. https://doi.org/10.1016/j.jpeds.2010.06.028 (Original work published 2010)