Identification of an interleukin HP1-like plasmacytoma growth factor produced by L cells in response to viral infection.
(1987) Journal of Immunology — Vol. 139, n° 9, p. 2965-2969 (1987)
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- Abstract
- We have recently purified and partially sequenced a new T cell-derived lymphokine with growth factor activity for B cell hybridomas and plasmacytomas, which we named interleukin HP1 (HP1). Here we show that, in response to viral infection or after treatment with poly(rI).poly(rC), L cells produce a factor that is capable of supporting the in vitro growth and survival of HP1-dependent cell lines. Serologic and structural evidence is presented in favor of the identity between the fibroblast factor and HP1, demonstrating that non-T cells can make HP1-related molecules.
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Cayphas, S., Van Damme, J., Vink, A., Simpson, R. J., Billiau, A., & Van Snick, J. (1987). Identification of an interleukin HP1-like plasmacytoma growth factor produced by L cells in response to viral infection. Journal of Immunology, 139(9), 2965-2969. https://hdl.handle.net/2078.5/33347 (Original work published 1987)