A range of polysubstituted tetrahydropyrans can be readily assembled by a novel methodology involving a metallo-ene reaction coupled with an intramolecular Sakurai cyclisation (IMSC) (C) 2000 Elsevier Science Ltd. All rights reserved.
Marko, I., & Leroy, B. (2000). Concise and stereocontrolled synthesis of polysubstituted tetrahydropyrans. Tetrahedron Letters, 41(37), 7225-7230. https://doi.org/10.1016/S0040-4039(00)01179-5 (Original work published 2000)