Role of the thymus in transplantation tolerance in miniature swine: II. Effect of steroids and age on the induction of tolerance to class I mismatched renal allografts.
(1999) Transplantation — Vol. 67, n° 3, p. 458-467 (1999)
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- Authors
- Abstract
- Recent studies in young (5-7 months) miniature swine have demonstrated that the thymus is involved in the rapid induction of stable tolerance to class I mismatched renal allografts after a 12-day course of Cyclosporine (CyA). Because both steroids and age are known to influence the structure and function of the thymus, we have now studied the effects of these two parameters on tolerance induction in this model.
- Affiliations
Harvard Medical School Transplantation biology research center, MGH, Boston
Citations
Yamada, K., Gianello, P., Ierino, F. L., Fishbein, J., Lorf, T., Shimizu, A., Colvin, R. B., & Sachs, D. H. (1999). Role of the thymus in transplantation tolerance in miniature swine: II. Effect of steroids and age on the induction of tolerance to class I mismatched renal allografts. Transplantation, 67(3), 458-467. https://hdl.handle.net/2078.5/191343 (Original work published 1999)