3-dimensional Architectures of Peritoneal Endometriosis
Donnez, Jacques;Nisolle, M.;Casanasroux, F.
(1992) Fertility and Sterility — Vol. 57, n° 5, p. 980-983 (1992)
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Donnez, JacquesUCLouvain
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Nisolle, M.
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Casanasroux, F.
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Abstract
Objective: To elucidate some biological characteristics of peritoneal endometriosis. Design: A recently advanced stereographic computer technology was applied for the investigation of the three-dimensional (3-D) architectures of peritoneal endometriosis. Setting: University Hospital of Gynecology. Patients: Biopsies were taken from 42 women with peritoneal endometriosis. Twenty-six of them were in the luteal phase. Seventeen of them received Zoladex (ICI, Cambridge, United Kingdom) for 12 weeks before biopsy. Results: Two different main types could be identified according to the presence or absence of ramifications. The apparently multifocal occurrence (in 2-D) of glandular epithelium was not confirmed by the 3-D study that showed that all epithelial glands are interconnected by luminal structures in each peritoneal lesion. Stereometric study suggests a stronger effect of gonadotropin-releasing hormone agonist therapy on the stroma than on the epithelium. Conclusions: The study evaluated the 3-D architectures of peritoneal endometriosis and identified two principal types of peritoneal endometriosis.
Donnez, J., Nisolle, M., & Casanasroux, F. (1992). 3-dimensional Architectures of Peritoneal Endometriosis. Fertility and Sterility, 57(5), 980-983. https://hdl.handle.net/2078.5/43513 (Original work published 1992)