Granulomatosis with polyangiitis with breast involvement mimicking metastatic cancer: Case report and literature review.
(2020) European journal of rheumatology — Vol. 7, n° 1, p. 41-43 (2020)
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- Authors
Gadeyne, Laura 
Henckaerts, Liesbet Goffin, Karolien E Floris, Giuseppe
- Abstract
- Granulomatosis with polyangiitis (GPA) is a systemic inflammatory disease, characterized by the presence of necrotizing vasculitis of small and medium-sized vessels, granulomatous inflammation and anti-neutrophil cytoplasmic antibodies (ANCAs). The diagnosis can be challenging due to the variable clinical presentation and possible involvement of virtually all organ systems. A correct diagnosis is indispensable for a timely start of medical treatment and to avoid unnecessary surgery. Therefore, cooperation with and the input of the pathologist is crucial. We report a case of a woman presenting with suspected metastatic cancer. The diagnosis of GPA was made mainly based on breast biopsy, and the patient was treated accordingly, with full recovery. This report provides a case description and a brief review of the literature.
- Affiliations
UZ Leuven Department of Nuclear Medicine
Citations
Gadeyne, L., Henckaerts, L., Goffin, K. E., Gheysens, O., Lerut, E., Roskams, T., Blockmans, D., & Floris, G. (2020). Granulomatosis with polyangiitis with breast involvement mimicking metastatic cancer: Case report and literature review. European journal of rheumatology, 7(1), 41-43. https://doi.org/10.5152/eurjrheum.2019.19065 (Original work published 2020)