Inhibitory effect of dietary innulin or oligofructose on the development of cancer metastases

Taper, HS.;Roberfroid, MB.
(2000) Anticancer Research : international journal of cancer research and treatment — Vol. 20, n° 6B, p. 4291-4294 (2000)

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  • Taper, HS.
    Author
  • Roberfroid, MB.
    Author
Abstract
The possible influence of continuous dietary treatment with 15% inulin ol oligofructose on the development of lung metastases of a transplantable liver tumor in young male C3H mice was investigated. Microscopical examination demonstrated a distinct inhibitory effect of this dietary treatment on the development of lung metastases of this tumor. There were 59% of mice bearing lung metastases in the control group, 36% in the inulin fed group and 35% in the oligofructose fed group. The total number of lung metastases was 37 in the control group, 18 in inulin fed and 6 in oligofructose fed mice. Several possible, mechanisms hypothetically involved in this astonishing inhibition of the development of lung metastases by dietary treatment with inulin or oligofructose are discussed.
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Taper, HS., & Roberfroid, MB. (2000). Inhibitory effect of dietary innulin or oligofructose on the development of cancer metastases. Anticancer Research : international journal of cancer research and treatment, 20(6B), 4291-4294. https://hdl.handle.net/2078.5/82376 (Original work published 2000)