Cerebral and Renal Arterial Thromboses in Systemic Lupus-erythematosus With Antiphospholipid Antibodies - a Report of 2 Cases

Balligand, Jean-Luc;Lefebvre, Chantal;Zenagui, D.;Coche, Edgard
(1990) Acta Clinica Belgica (Multilingual Edition) — Vol. 45, n° 6, p. 372-378 (1990)

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Authors
  • Balligand, Jean-Luc
    Author
  • Lefebvre, Chantal
    Author
  • Zenagui, D.
    Author
  • Coche, EdgardUCLouvain
    Author
Abstract
Antiphospholipid antibodies have been associated with an increased risk of thromboses, most of which occur in veins. We observed a very unusual association of cerebral and renal thromboses, in 2 patients with systemic lupus and anti-prothrombinase, in whom arterial occlusions were clearly documented. Immunosuppressive treatment was followed by a dramatic improvement in both. In the literature, no treatment clearly prevents the recurrence of these thromboses. This could be partly explained by our current ignorance of their pathogeny.
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Balligand, J.-L., Lefebvre, C., Zenagui, D., & Coche, E. (1990). Cerebral and Renal Arterial Thromboses in Systemic Lupus-erythematosus With Antiphospholipid Antibodies - a Report of 2 Cases. Acta Clinica Belgica (Multilingual Edition), 45(6), 372-378. https://hdl.handle.net/2078.5/81652 (Original work published 1990)