Antiphospholipid antibodies have been associated with an increased risk of thromboses, most of which occur in veins. We observed a very unusual association of cerebral and renal thromboses, in 2 patients with systemic lupus and anti-prothrombinase, in whom arterial occlusions were clearly documented. Immunosuppressive treatment was followed by a dramatic improvement in both. In the literature, no treatment clearly prevents the recurrence of these thromboses. This could be partly explained by our current ignorance of their pathogeny.
Balligand, J.-L., Lefebvre, C., Zenagui, D., & Coche, E. (1990). Cerebral and Renal Arterial Thromboses in Systemic Lupus-erythematosus With Antiphospholipid Antibodies - a Report of 2 Cases. Acta Clinica Belgica (Multilingual Edition), 45(6), 372-378. https://hdl.handle.net/2078.5/81652 (Original work published 1990)