Mise en place d’un système de surveillance moléculaire de la résistance aux antipaludiques en République Démocratique du Congo : rôle, avantages et défis
(2021)
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- Abstract
- Drug resistance is a major obstacle to malaria control in the DRC. Two systematic reviews and three original studies indicate widespread resistance of P. falciparum to chloroquine and sulfadoxine-pyrimethamine as well as an imminent risk of local emergence or dissemination of resistance to artemisinin from sub-regional foci. In addition, the epidemiological context prevailing in the country is marked by a significant socio-economic burden of malaria and significant socio-health disparities within the population. This results in inadequate therapeutic behaviors that can worsen drug resistance. The system put in place for the molecular surveillance of this resistance demonstrates considerable epidemiological advantages and feasibility in local conditions but remains prone to financial and organizational challenges for its effective implementation in the national antimalarial policy.
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Kayiba Kalenda, N. (2021). Mise en place d’un système de surveillance moléculaire de la résistance aux antipaludiques en République Démocratique du Congo : rôle, avantages et défis. https://hdl.handle.net/2078.5/113642