Dose comparisons of clopidogrel and aspirin in acute coronary syndromes.

Mehta, Shamir R;Bassand, Jean-Pierre;Chrolavicius, Susan;Diaz, Rafael;Dangoisse, Vincent;et.al.
(2010) New England Journal of Medicine — Vol. 363, n° 10, p. 930-942 (2010)

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Authors
  • Mehta, Shamir R
    Author
  • Bassand, Jean-Pierre
    Author
  • Chrolavicius, Susan
    Author
  • Diaz, Rafael
    Author
  • Dangoisse, VincentUCLouvain
    Collaborator
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Abstract
In patients with an acute coronary syndrome who were referred for an invasive strategy, there was no significant difference between a 7-day, double-dose clopidogrel regimen and the standard-dose regimen, or between higher-dose aspirin and lower-dose aspirin, with respect to the primary outcome of cardiovascular death, myocardial infarction, or stroke. (Funded by Sanofi-Aventis and Bristol-Myers Squibb; ClinicalTrials.gov number, NCT00335452.)
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Mehta, S. R., Bassand, J.-P., Chrolavicius, S., Diaz, R., Eikelboom, J. W., Fox, K. A. A., Granger, C. B., Jolly, S., Joyner, C. D., Rupprecht, H.-J., Widimsky, P., Afzal, R., Pogue, J., Yusuf, S., & CURRENT-OASIS. (2010). Dose comparisons of clopidogrel and aspirin in acute coronary syndromes. New England Journal of Medicine, 363(10), 930-942. https://doi.org/10.1056/NEJMoa0909475 (Original work published 2010)