Preservatives have been used for a long time mainly but not exclusively by cosmetic industries. The aim was obvious, but most companies did not take into account the potential allergenicity of preservatives. Different ones were launched on the market. The most popular were the parabens and the formaldehyde releasers, such as quaternium-15, 2,5-diazolidinyl urea (Germall II®) and imidazolidinyl urea (Germall 115®), and all of them displayed allergenic properties. [...]
Lachapelle, J.-M. (2020). Methylisothiazolinone: the new star of contact dermato-allergology. Journal of the European Academy of Dermatology and Venereology : JEADV, 34(2), 218. https://doi.org/10.1111/jdv.16174 (Original work published 2020)