Early diagnosis of immune heparin-induced thrombocytopenia (HIT) is essential to improve clinical outcome but remains challenging. The release of platelet microparticles (PMPs) is considered of major pathophysiological significance.
Mullier, F., MINET, V., Bailly, N., Devalet, B., Douxfils, J., Chatelain, C., Elalamy, I., Dogné, J. M., & Chatelain, B. (2014). Platelet microparticle generation assay: a valuable test for immune heparin-induced thrombocytopenia diagnosis. Thrombosis Research : vascular obstruction, hemorrhage and hemostasis, 133(6), 1068-1073. https://doi.org/10.1016/j.thromres.2013.12.009 (Original work published 2014)