Olfactory impairment has been linked with an increased risk of death in the aging population, yet the reasons behind it are unknown. Nowadays, effectively detecting vulnerable patients who will evolve poorly after surgery remains a complex task. In this thesis, we investigated whether olfactory dysfunction could be a reliable predictor of poor postoperative outcome in older patients. Also, we aimed to identify the potential underpinning mechanisms, notably by exploring the connection with frailty, cognition, and telomere length. In the end, we propose a new angle on the concept of frailty, the presumed culprit making the bridge between olfactory impairment and poor outcome. Furthermore, we discuss the unique and promising place of olfactory testing in tomorrow’s perioperative world.
Van Regemorter, V. (2024). Sniffin’ odors in the aging population? Smells like a new way to predict postoperative outcome! https://hdl.handle.net/2078.5/272823