Right-to-left intracardiac shunt through a patent foramen ovale sometimes induces a significant arterial oxygen desaturation. We describe two cases of severe hypoxia due to a patent foramen ovale, treated successfully by transcatheter closure of the intracardiac shunt. One case occurred after implantation of a cardiac assist device, the other patient presented with a platypnoeaorthodeoxia syndrome. Clinical considerations are outlined.
Faes, D., Gilles, R., & Kefer, J. (2009). Transcatheter patent foramen ovale closure: a treatment for refractory hypoxaemia. Acta Cardiologica : an international journal of cardiology, 64(4), 561-563. https://doi.org/10.2143/AC.64.4.2041626 (Original work published 2009)