Allopurinol is the most common cause of Stevens-Johnson syndrome and toxic epidermal necrolysis in Europe and Israel.

Halevy, Sima;Ghislain, Pierre-Dominique;Mockenhaupt, Maja;Fagot, Jean-Paul;Roujeau, Jean-Claude;et.al.
(2008) Journal of the American academy of dermatology — Vol. 58, n° 1, p. 25-32 (2008)

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Authors
  • Halevy, Sima
    Author
  • Mockenhaupt, Maja
    Author
  • Fagot, Jean-Paul
    Author
  • Roujeau, Jean-Claude
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Abstract
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare severe cutaneous adverse reactions.
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Citations

Halevy, S., Ghislain, P.-D., Mockenhaupt, M., Fagot, J.-P., Bouwes Bavinck, J. N., Sidoroff, A., Naldi, L., Dunant, A., Viboud, C., & Roujeau, J.-C. (2008). Allopurinol is the most common cause of Stevens-Johnson syndrome and toxic epidermal necrolysis in Europe and Israel. Journal of the American academy of dermatology, 58(1), 25-32. https://doi.org/10.1016/j.jaad.2007.08.036 (Original work published 2008)