Brain glucose utilization in childhood Huntington's disease studied with positron emission tomography (PET).

De Volder, Anne;Bol, Anne;Michel, Christian;Cogneau, M.;Goffinet, André;et.al.
(1988) Brain & Development — Vol. 10, n° 1, p. 47-50 (1988)

Files

No attached file found for this publication.

Details

Authors
  • De Volder, AnneUCLouvain
    Author
  • Bol, AnneUCLouvain
    Author
  • Michel, ChristianUCLouvain
    Collaborator
  • Cogneau, M.
    Author
  • Author
  • Lyon, GillesUCLouvain
    Author
  • Goffinet, AndréUCLouvain
    Author
Show more
Abstract
Brain glucose metabolism was measured in two children with early-onset Huntington's disease, using positron emission tomography with fluorodeoxyglucose (FDG) as the tracer. A marked (48%) hypometabolism was found at the level of the caudate nuclei, but other areas of the brain, particularly the cerebral cortex, were not significantly affected. Despite its different clinical presentation, Huntington's disease in children is characterized by brain metabolic alterations similar to those found in adult patients.
Affiliations

Citations

De Volder, A., Bol, A., Cogneau, M., Evrard, P., Lyon, G., & Goffinet, A. (1988). Brain glucose utilization in childhood Huntington’s disease studied with positron emission tomography (PET). Brain & Development, 10(1), 47-50. https://hdl.handle.net/2078.5/138233 (Original work published 1988)