Cyclosporine A in five children with severe aplastic anemia.

Neira, L;Vermylen, Christiane;Ninane, J.;Doyen, Chantal;Cornu, Guy
(1990) Pediatric Hematology & Oncology —

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  • Neira, L
    Author
  • Vermylen, ChristianeUCLouvain
    Author
  • Ninane, J.
    Author
  • Doyen, ChantalUCLouvain
    Author
  • Cornu, GuyUCLouvain
    Author
Abstract
Five children with aplastic anemia (AA) were treated with Cyclosporine A (CyA) after failure or poor response to other immunosuppressive agents. A complete remission was achieved in 3 patients, a good partial response in 1, and a poor partial response in another. In 1 patient in whom a complete remission was obtained, a relapse occurred 4 months after CyA was stopped. The treatment was resumed and a complete remission was again observed. Four patients were still on treatment, and side effects were mild. CyA appeared to be an effective treatment in AA.
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Neira, L., Vermylen, C., Ninane, J., Doyen, C., & Cornu, G. (1990). Cyclosporine A in five children with severe aplastic anemia. Pediatric Hematology & Oncology. https://doi.org/10.3109/08880019009034322