Hyperthermia complicating tricyclic antidepressant overdose.

Hantson, Philippe;Benaissa, Lamine;Clemessy, Jean-Luc;Baud, Frédéric J
(1996) Intensive Care Medicine — Vol. 22, n° 5, p. 453-455 (1996)

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Authors
  • Hantson, PhilippeUCLouvain
    Author
  • Benaissa, Lamine
    Author
  • Clemessy, Jean-Luc
    Author
  • Baud, Frédéric J
    Author
Abstract
We observed a 51-year-old woman who was admitted for severe amitriptyline overdose. Besides major cardiovascular complications, the patient developed severe hyperpyrexia with a central body temperature of more than 43 degrees C for 5 h. The patient died on day 3 from cardiocirculatory collapse and arrhythmias. Hyperthermia was unresponsive to cooling with ice water, gastric lavage, muscle relaxation, and dantrolene and bromocriptine administration. The possible mechanisms of refractory hyperthermia are discussed.
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Hantson, P., Benaissa, L., Clemessy, J.-L., & Baud, F. J. (1996). Hyperthermia complicating tricyclic antidepressant overdose. Intensive Care Medicine, 22(5), 453-455. https://hdl.handle.net/2078.5/54644 (Original work published 1996)