Prevalence of Helicobacter pylori infection in children in Ho Chi Minh city in Vietnam and risk factors
(2023)
Files
Manuscript_HpyloriinchildreninVietnam_PhDCheHoangThai_finalversion.pdf
Open Access - Adobe PDF
- 4.73 MB
Details
- Authors
- Supervisors
- Robert, Annie
- Abstract
- Helicobacter pylori (H. pylori) infection in children has shown to be a threat in Asian cities, reaching 77% in Hanoi in recent years. Such information was not available in Ho Chi Minh city (HCMC), despite its gastric cancer risk. Our thesis aimed to assess the burden of H. pylori in children in HCMC, its geographical distribution, and risk factors. We conducted a school-based cross-sectional study in HCMC. A total of 1476 children from 48 public schools (216 classes) across 24 districts of HCMC were enrolled. We found that H. pylori infection is highly prevalent (87.7%), and increased with crowded density. Younger age, crowded living conditions, and poor hygienic practices were associated with a higher prevalence of H. pylori infection. High rates of antimicrobial resistance among antibiotics used for H. pylori treatment were also observed in clinical studies. These findings highlight a fecal-oral route for transmission. Crowded living conditions and high rates of antibiotic resistance favor a high H. pylori infection rate. Therefore, national politics against antibiotic resistance are needed. Preventive programs should be set up with a focus on education of the whole population for good hygiene practices.
- Affiliations
Citations
Che Hoang, T. (2023). Prevalence of Helicobacter pylori infection in children in Ho Chi Minh city in Vietnam and risk factors. https://hdl.handle.net/2078.5/102142