Bortezomib-induced histiocytoid Sweet syndrome

Murase, Jenny E.;Théate, Ivan;Wu, Jashin J.;Cole, Gary W.;Dyson, Senait W.;et.al.
(2009) Journal of the American academy of dermatology — Vol. 60, n° 3, p. 496-497 (2009)

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Authors
  • Murase, Jenny E.
    Author
  • Théate, IvanUCLouvain
    Author
  • Wu, Jashin J.
    Author
  • Cole, Gary W.
    Author
  • Dyson, Senait W.
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Abstract
Bortezomib, a proteasome inhibitor approved for the treatment of multiple myeloma, has been reported to be associated with Sweet syndrome. However, careful review of the histopathology of the first reported case and our case revealed similar histologic and immunohistochemical findings (a mononuclear dermal infiltrate) and not the usual neutrophilic infiltrate of Sweet syndrome. We suggest that the dermatitis induced by bortezomib is best classified as "histiocytoid Sweet syndrome." (J Am Acad Dermatol 2009;60:496-7.)
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Citations

Murase, J. E., Théate, I., Wu, J. J., Cole, G. W., Barr, R. J., & Dyson, S. W. (2009). Bortezomib-induced histiocytoid Sweet syndrome. Journal of the American academy of dermatology, 60(3), 496-497. https://doi.org/10.1016/j.jaad.2008.09.007 (Original work published 2009)