Limited effects of activated protein C on red blood cell deformability.

Piagnerelli, Michael;Njimi, Hassane;Coelho, Tatiana Veloso;Reggiori, Giulia;Vincent, Jean-Louis;et.al.
(2013) Clinical hemorheology and microcirculation — Vol. 53, n° 4, p. 387-391 (2013)

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Authors
  • Piagnerelli, Michael
    Author
  • Njimi, Hassane
    Author
  • Coelho, Tatiana Veloso
    Author
  • Reggiori, Giulia
    Author
  • Castanares Zapatero, DiegoUCLouvain
    Author
  • Vincent, Jean-Louis
    Author
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Abstract
Alterations of the microcirculation are common in critically ill patients and persistence of these alterations is associated with poor outcome. Infusion of high doses of activated protein C can ameliorate the microcirculation. Because red blood cells (RBCs) play an essential role in oxygen transport to the tissues, we studied the effects of activated protein C on RBC deformability in septic patients.
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Piagnerelli, M., Njimi, H., Coelho, T. V., Reggiori, G., Castanares Zapatero, D., Donadello, K., & Vincent, J.-L. (2013). Limited effects of activated protein C on red blood cell deformability. Clinical hemorheology and microcirculation, 53(4), 387-391. https://doi.org/10.3233/CH-2012-1550 (Original work published 2013)