Accumulation of polychlorinated biphenyls in adipocytes: selective targeting to lipid droplets and role of caveolin-1
(2012) PLoS One — Vol. 7, n° 2, p. e31834 (2012)
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- Abstract
- Background : Polychlorinated biphenyls (PCBs) are persistent environmental pollutants that preferentially accumulate in lipid-rich tissues of contaminated organisms. Although the adipose tissue constitutes a major intern reservoir of PCBs and recent epidemiological studies associate PCBs to the development of obesity and its related disorders, little is known about the mechanisms involved in their uptake by the adipose tissue and their intracellular localization in fat cells.
- Affiliations
Université de Liège Laboratoire d'Ecologie animale et d'Ecotoxicologie
Citations
Bourez, S., Le Lay, S., Van Den Daelen, C., Louis, C., Larondelle, Y., Thomé, J.-P., Schneider, Y.-J., Dugail, I., & Debier, C. (2012). Accumulation of polychlorinated biphenyls in adipocytes: selective targeting to lipid droplets and role of caveolin-1. PLoS One, 7(2), e31834. https://doi.org/10.1371/journal.pone.0031834 (Original work published 2012)