Mycobacterium-tuberculosis in Household Contacts of Human-immunodeficiency-virus Type-1-seropositive Patients With Active Pulmonary Tuberculosis in Kinshasa, Zaire
(1993) The Journal of Infectious Diseases — Vol. 168, n° 1, p. 106-111 (1993)
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- Abstract
- Rates of infection with Mycobacterium tuberculosis were compared in Kinshasa, Zaire, in 521 household contacts of 74 human immunodeficiency virus type 1 (HIV-1)-seropositive index patients and in 692 household contacts of 95 HIV-1-seropositive index patients with sputum smear-positive pulmonary tuberculosis: No difference was noted between contacts of HIV-1-seropositive and -seronegative patients. The increasing prevalence of M. tuberculosis infection with increasing age was similar in household contacts of seropositive and seronegative patients; by age 16 years, 75% were purified protein derivative-positive. The similarly low rates of M. tuberculosis infection in household contacts of HIV-1-seropositive and -seronegative index patients with sputum smear-positive pulmonary tuberculosis indicates that HIV-1-seropositive patients with pulmonary tuberculosis are not more infectious than HIV-1-seronegative patients with pulmonary tuberculosis.
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Klausner, JD., Ryder, RW., Baende, E., Lelo, U., Williame, JC., Ngamboli, K., Perriëns, J. H., Kaboto, M., & Prignot, J. (1993). Mycobacterium-tuberculosis in Household Contacts of Human-immunodeficiency-virus Type-1-seropositive Patients With Active Pulmonary Tuberculosis in Kinshasa, Zaire. The Journal of Infectious Diseases, 168(1), 106-111. https://hdl.handle.net/2078.5/146991 (Original work published 1993)