beta-Aminophosphonic compounds derived from methyl 1-dimethoxyphosphoryl-2-succinimidocyclohex-3-ene-1-carboxylates

Defacqz, Nathalie;Touillaux, Roland;Cordi, Alex;Marchand-Brynaert, Jacqueline
(2001) Royal Chemical Society. Journal. Perkin Transactions 1 — n° 20, p. 2632-2637 (2001)

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  • Defacqz, NathalieUCLouvain
    Author
  • Touillaux, RolandUCLouvain
    Author
  • Cordi, AlexInstitut de Recherches Servier, Suresnes, France
    Author
  • Marchand-Brynaert, JacquelineUCLouvain
    Author
Abstract
Compounds 3a,b, the [4 + 2] cycloadducts of trimethyl 2-phosphonoacrylate and N-buta-1,3-dienylsuccinimide, have been transformed into various beta -aminophosphonic acid derivatives 4-17 by selective deprotection, epoxidation, dihydroxylation, and oxidative cleavage of the cyclohexenyl C-C double bond.
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Defacqz, N., Touillaux, R., Cordi, A., & Marchand-Brynaert, J. (2001). beta-Aminophosphonic compounds derived from methyl 1-dimethoxyphosphoryl-2-succinimidocyclohex-3-ene-1-carboxylates. Royal Chemical Society. Journal. Perkin Transactions 1, 20, 2632-2637. https://doi.org/10.1039/b105111n (Original work published 2001)