Indications and administration of intra-amniotic infusions of L-thyroxine in the context of non-immune fetal hypothyroidism with goiter lack of standardization. Systematic follow-up of clinical features related to thyroid hormonal homeostasis may be useful to evaluate their efficiency and develop standardized management guidelines.
Polle, O., Gheldof, A., Lysy, P., & Bernard, P. (2021). Intra-amniotic levothyroxine infusions in a case of fetal goiter due to novel gene variants. Clinical Case Reports, 9(9), e04565 [1-7]. https://doi.org/10.1002/ccr3.4565 (Original work published 2021)