[Research priorities to drug irradiation]
(1996) 7th Meeting on Irradiation Chemistry — Location: CAEN(France) (5.September.1994)
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- Abstract
- The radiation treatment of bulk quantities with the transport system causes special difficulties like reliable dosimetry, dose-effect relationship, homogeneity of dose distribution, allowable ratio between the maximum and the minimum doses, modified atmosphere packaging,... All irradiated drugs undergo flavour and color changes, it is important to continue the collection of radiolytic by products and the investigations about the chemistry of these products acid to expand the toxicological studies. Improvement of microbiological safety, shelflife extension and replacement of chemical treatment for heat sensitive drug, are some reasons for radiosterilization!
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Citations
Tilquin, B., & Rollmann, B. (1996). [Research priorities to drug irradiation]. Journal de Chimie Physique, 93(1), 224-230. https://hdl.handle.net/2078.5/144324 (Original work published 1996)