Isolation and purification of panarine, A. Alkaloid from a Venezuelan Curare

Quetin-Leclercq, Joëlle;Angenot, Luc;Dupont, Léon;Bisset, Norman G.
(1988) Phytochemistry — Vol. 27, n° 12, p. 4002-4004 (1988)

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High Speed Counter Current Chromatography (HSCCC) has been used to isolate and purify two quaternary alkaloids from a sample of curare prepared by the Panare Indians of Estado Bolivar, Venezuela. One of the compounds is the known base macusine B (1). The other one is a new but related base named panarine (2). Its structure has been established unequivocally by spectral and X-ray crystallographic analysis.
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Quetin-Leclercq, J., Angenot, L., Dupont, L., & Bisset, N. G. (1988). Isolation and purification of panarine, A. Alkaloid from a Venezuelan Curare. Phytochemistry, 27(12), 4002-4004. https://doi.org/10.1016/0031-9422(88)83075-9 (Original work published 1988)