Using a cDNA probe, two genomic clones were obtained encoding the human tissue inhibitor of metalloproteinases-3 (TIMP-3). Analysis of these clones showed that they contained four distal exons and three introns of the gene. Although the intron-exon structure is similar to that of the timp1 gene, the first intron of the timp3 gene is much longer, being at least 17.5 kb in size.
Hammani, K., Henriet, P., Silbiger, S. M., & DeClerck, Y. A. (1996). Cloning and partial structure of the gene encoding human tissue inhibitor of metalloproteinases-3. Gene, 170(2), 287-288. https://hdl.handle.net/2078.5/204260 (Original work published 1996)