Increased activation of nuclear factor-kappa B (NF-kappaB) in isolated peritoneal macrophages of patients with endometriosis.

Lousse, Jean-Christophe;Van Langendonckt, Anne;González-Ramos, Reinaldo;Defrere, Sylvie;Donnez, Jacques;et.al.
(2008) Fertility and sterility — Vol. 90, n° 1, p. 217-220 (2008)

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Authors
  • Lousse, Jean-ChristopheUCLouvain
    Author
  • Van Langendonckt, AnneUCLouvain
    Author
  • González-Ramos, Reinaldo
    Author
  • Defrere, SylvieUCLouvain
    Author
  • Renkin, EmmanuelleUCLouvain
    Author
  • Donnez, JacquesUCLouvain
    Author
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Abstract
Endometriosis is characterized by pelvic inflammation that shows an increased number of activated peritoneal macrophages and their secreted products such as cytokines, growth factors, and angiogenic factors. Our results show that activation of nuclear factor-kappa B (NF-kappaB), a pro-inflammatory transcription factor, is statistically significantly increased in peritoneal macrophages from patients with endometriosis when compared with controls.
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Citations

Lousse, J.-C., Van Langendonckt, A., González-Ramos, R., Defrere, S., Renkin, E., & Donnez, J. (2008). Increased activation of nuclear factor-kappa B (NF-kappaB) in isolated peritoneal macrophages of patients with endometriosis. Fertility and sterility, 90(1), 217-220. https://doi.org/10.1016/j.fertnstert.2007.06.015 (Original work published 2008)