Aspirin Misuse At Home According To START And STOPP In Frail Older Persons

(2012) 8th Congress of the European Union Geriatric Medicine Society — Location: Brussels (26.September.2012)

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Background. Aspirin misuse is concerned by three and six criteria of the START and STOPP lists, which help detecting inappropriate prescribing in older people. This study described aspirin misuse and aspirin-related hospital admissions in this population. Methods. Data were collected upon acute hospital admission in frail older persons (≥75 years; ISAR≥2/6). Using the START and STOPP criteria, a pharmacist and a geriatrician independently detected events of prescribing omission (PO) and inappropriate medication (IM) concerning drugs at home, and determined whether the hospital admission was related to PO or IM. Results. In 302 frail older persons (84±5 years; ♀63%), 77 of the 362 PO were aspirin underuse (lack of aspirin in patients in secondary cardiovascular (CV) prevention and sinus rhythm, n=41; with diabetes and coexisting CV risk factor, n=33; or with chronic atrial fibrillation and contraindicated warfarin, n=3), while 35 of the 210 detected IM were aspirin overuse (dose>150mg/d, n=25; aspirin in primary CV prevention, n=7; aspirin and peptic ulcer disease history without gastric protection, n=2; aspirin and warfarin without gastric protection, n=1). Overall, 82 hospital admissions were related to inappropriate prescribing, of which 8 were linked to aspirin misuse (aspirin underuse and admission for myocardial ischaemia in secondary CV prevention, n=6; aspirin overuse and admissions for haemorrhage, n=2). Conclusions. Aspirin misuse at home was detected in about one third of these frail older persons and accounted for 10% of the hospital admissions related to inappropriate prescribing. Clinicians should remember when to consider and to avoid aspirin in this frail population
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Dalleur, O., Boland, B., & Spinewine, A. (2012). Aspirin Misuse At Home According To START And STOPP In Frail Older Persons. 8th Congress of the European Union Geriatric Medicine Society, Brussels. https://hdl.handle.net/2078.5/230198