Release of nickel into fluid stored in the reservoir of Dermo-Jets.

Lachapelle, Jean-Marie;Tennstedt, Dominique;Lauwerys, Robert;Cromphaut, P.;Armijo, F.
(1982) Contact dermatitis — Vol. 8, n° 2, p. 122-127 (1982)

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Authors
  • Lachapelle, Jean-MarieUCLouvain
    Author
  • Tennstedt, DominiqueUCLouvain
    Author
  • Lauwerys, RobertUCLouvain
    Author
  • Cromphaut, P.
    Author
  • Armijo, F.
    Author
Abstract
Release of nickel into triamcinolone acetonide suspensions stored in the reservoir of a Dermo-Jet was demonstrated by electrothermal atomic absorption spectrometry. Increased urinary nickel excretion was found for three days following intradermal injections (with the Dermo-Jet) of triamcinolone acetonide in patients suffering from alopecia areata. The dimethylglyoxime test showed that the internal rod of the reservoir as well as metallic internal parts of the nozzle leached appreciable amounts of nickel, even before any clinical use.
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Citations

Lachapelle, J.-M., Tennstedt, D., Lauwerys, R., Cromphaut, P., & Armijo, F. (1982). Release of nickel into fluid stored in the reservoir of Dermo-Jets. Contact dermatitis, 8(2), 122-127. https://doi.org/10.1111/j.1600-0536.1982.tb04157.x (Original work published 1982)