Cellular pharmacokinetics and intracellular activity against Listeria monocytogenes and Staphylococcus aureus of chemically modified and nanoencapsulated gentamicin.

Imbuluzqueta, Edurne;Lemaire, Sandrine;Gamazo, Carlos;Elizondo, Elisa;Blanco-Prieto, María J;et.al.
(2012) Journal of Antimicrobial Chemotherapy — Vol. 67, n° 9, p. 2158-2164 (2012)

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Authors
  • Imbuluzqueta, Edurne
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  • Lemaire, Sandrine
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  • Gamazo, Carlos
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  • Elizondo, Elisa
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  • Blanco-Prieto, María J
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Abstract
GEN-AOT formulations yielded a high cellular accumulation, especially in the cytosol, which resulted in improved efficacy against both intracellular S. aureus and L. monocytogenes.
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Imbuluzqueta, E., Lemaire, S., Gamazo, C., Elizondo, E., Ventosa, N., Veciana, J., Van Bambeke, F., & Blanco-Prieto, M. J. (2012). Cellular pharmacokinetics and intracellular activity against Listeria monocytogenes and Staphylococcus aureus of chemically modified and nanoencapsulated gentamicin. Journal of Antimicrobial Chemotherapy, 67(9), 2158-2164. https://doi.org/10.1093/jac/dks172 (Original work published 2012)