Development and Validation of the Behavioral Determinants of Deprescribing Questionnaire (BDDQ)

Alves Jorge, Sara;Van den Broucke, Stephan;De Saint-Hubert, Marie;Spinewine, Anne
(2026) Patient Preference and Adherence — Vol. Volume 20, p. 1-18 (2026)

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Abstract
Purpose: Deprescribing is a strategy to optimize medication use. While a patient’s willingness to engage in deprescribing depends onseveral factors, the literature on the subject relies almost exclusively on questionnaires that only measure patients’ attitudes towardsdeprescribing. This study used health behavior theories (HBTs) to develop a questionnaire that measures a larger range of psycho-logical determinants of patients’ deprescribing participation.Patient and Methods: A draft self-report questionnaire was developed based on a recent systematic review. It measures 11dimensions representing the main HBT-derived determinants of patients’ participation in deprescribing, as well as previous experiencewith deprescribing, current behavior, and intention to participate in deprescribing. Face validity was assessed via small groupdiscussions involving 10 healthcare professionals and 12 older people. Construct validity was assessed in a sample of 103 participants,using exploratory factor analysis (EFA). Internal consistency was assessed via Cronbach’s alpha and Omega coefficient.Results: The EFA confirmed 11 dimensions explaining 67,15% of the total variance but revealed poor factor loadings for some itemsand low Cronbach alpha values (<.50) for three factors. Removal of items and factors resulted in a final questionnaire of 25 itemsmeasuring 8 conceptually relevant dimensions, with internal consistencies ranging between.55 and.77: perceived necessity ofmedication, perceived risks of medication, perceived norms regarding medication use, perceived effects of deprescribing, perceiveddifficulty of deprescribing, perceived social support, healthcare system support, and medication literacy.Conclusion: A conceptually based and psychometrically validated questionnaire was developed measuring the main behavioraldeterminants of older patients’ participation in deprescribing, allowing a comprehensive investigation of intentions and behavior.Keywords: medication management, health behavior theories, older adults, psychometric properties
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Alves Jorge, S., Van den Broucke, S., De Saint-Hubert, M., & Spinewine, A. (2026). Development and Validation of the Behavioral Determinants of Deprescribing Questionnaire (BDDQ). Patient Preference and Adherence, Volume 20, 1-18. https://doi.org/10.2147/ppa.s576446 (Original work published 2026)