Comparison of Enterotoxin Production, Cytotoxin Production, Serogrouping, and Antimicrobial Susceptibilities of Clostridium-difficile Strains Isolated From Aids and Human Immunodeficiency Virus-negative Patients

Barbut, F.;Delmée, Michel;Depitre, C.;Corthier, G.;Petit, JC.
(1993) Journal of Clinical Microbiology — Vol. 31, n° 3, p. 740-742 (1993)

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  • Barbut, F.
    Author
  • Delmée, MichelUCLouvain
    Author
  • Depitre, C.
    Author
  • Corthier, G.
    Author
  • Petit, JC.
    Author
Abstract
We analyzed and compared Clostridium difficile strains isolated from diarrheic stools of 49 human immunodeficiency virus (HIV)-negative and 50 AIDS patients. Our results suggest that distribution patterns of serogroups are different in these two populations. Serogroup C (which has been previously reported to be very resistant to antimicrobial agents) represents 66.0 and 18.4% of the isolates from AIDS and HIV-negative patients, respectively (P < 0.001); the selection of serogroup C could be explained by multiple antibiotic pressure to which AIDS patients have been subjected.
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Barbut, F., Delmée, M., Depitre, C., Corthier, G., & Petit, JC. (1993). Comparison of Enterotoxin Production, Cytotoxin Production, Serogrouping, and Antimicrobial Susceptibilities of Clostridium-difficile Strains Isolated From Aids and Human Immunodeficiency Virus-negative Patients. Journal of Clinical Microbiology, 31(3), 740-742. https://hdl.handle.net/2078.5/147244 (Original work published 1993)