The case is reported of a patient with a symptomatic thrombophilic status and a positivity for both direct and indirect antiglobulin tests who underwent mitral valve replacement. Because of the antiglobulin test positivity, the patient was enrolled in a preoperative autologous blood donation program in order to avoid exposure to allogenic blood. The operation was successful, and the postoperative course uneventful; the patient was discharged on postoperative day 6 and prescribed oral anticoagulation. This case suggests that a safe valve replacement can be carried out even in the presence of a symptomatic thrombophilic preoperative status.
Mastrobuoni, S., Avvisati, G., Tirindelli, M. C., Migliaccio, M., Chello, M., & Covino, E. (2005). Mitral valve replacement in a patient with severe thrombophilic status and direct antiglobulin test positivity: case report. The Journal of Heart Valve Disease, 14(2), 268-270. https://hdl.handle.net/2078.5/126791 (Original work published 2005)