Photodynamic therapy for subfoveal classic choroidal neovascularization related to punctate inner choroidopathy (PIC) or presumed ocular histoplasmosis-like syndrome (POHS-like)

Postelmans, L;Snyers, Bernadette;Pasteels, B;Coquelet, P.;Smets, E.;et.al.
(2005) 7th International Symposium on Ocular Inflammation — Location: Padova (Italy)

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  • Postelmans, L
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  • Snyers, BernadetteUCLouvain
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  • Pasteels, B
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  • Coquelet, P.
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  • Smets, E.
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Abstract
Purpose : To evaluate the safety and efficacy of photodynamic therapy with verteporfin (PDT) for subfoveal classic choroidal neovascularization (CNV) related to punctate inner choroidopathy (PIC) or presumed ocular histoplasmosis-like syndrome (POHS-like). Methods : Retrospective review of 16 eyes from 14 patients with subfoveal classic CNV associated with PIC or POHS-like and treated with PDT. Results : The mean visual acuity increased from 4.5/10 (range: 1/10-9/10) to 7/10 (range: 2/10-10/10) after a mean follow-up of 21 months (range: 8-32 months) and a mean number of 2 PDT (range: 1-6). Visual acuity remained stable or improved in 13 of the 16 eyes (81%) and decreased in three. Conclusion : This nearly two-year follow-up study suggests that PDT could be helpful for patients with subfoveal classic CNV related to PIC or POHS-like.
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Postelmans, L., Snyers, B., Pasteels, B., Coquelet, P., Caspers, L., Verougstraete, C., Leys, A., Wirix, M., Mauget-Faysse, M., Quaranta, M., Rolland, F., & Smets, E. (2005). Photodynamic therapy for subfoveal classic choroidal neovascularization related to punctate inner choroidopathy (PIC) or presumed ocular histoplasmosis-like syndrome (POHS-like). Ocular Immunology and Inflammation, 13(5), 361-366. https://doi.org/10.1080/09273940590951124 (Original work published 2005)