Microliter-scale in vitro aerosol-cell delivery of inhalable antisense oligonucleotide (aso) induces “Burst-like” Pharmacokinetics

Kumar, Pramod; Chakraborty, Ashesh; Richter, Elias; Yang, Lin; Schröppel, Andreas; Mergault, Coralie; Blayac, Marion; Vanbever, Rita; Plantier, Laurent; Heuzé-Vourch, Nathalie; Schmid, Otmar

doi:10.1016/j.ijpx.2026.100588

Microliter-scale in vitro aerosol-cell delivery of inhalable antisense oligonucleotide (aso) induces “Burst-like” Pharmacokinetics

Kumar, Pramod

;

Chakraborty, Ashesh

;

Richter, Elias

;

Yang, Lin

;

Schmid, Otmar

;et.al.

(2026) International Journal of Pharmaceutics: — p. 100588 (2026)

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Authors

Kumar, Pramod
Author
Chakraborty, Ashesh
Author
Richter, Elias
Author
Yang, Lin
Author
Vanbever, RitaUCLouvain
Author
Schmid, Otmar
Author

Abstract

Please cite this article as: P. Kumar, A. Chakraborty, E. Richter, et al., Microliter-scale in vitro aerosol-cell delivery of inhalable antisense oligonucleotide (aso) induces "Burst-like" Pharmacokinetics, (2026), https://doi.

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UCLouvainSSS/LDRI - Louvain Drug Research Institute

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Kumar, P., Chakraborty, A., Richter, E., Yang, L., Schröppel, A., Mergault, C., Blayac, M., Vanbever, R., Plantier, L., Heuzé-Vourch, N., & Schmid, O. (2026). Microliter-scale in vitro aerosol-cell delivery of inhalable antisense oligonucleotide (aso) induces “Burst-like” Pharmacokinetics. International Journal of Pharmaceutics:, 100588. https://doi.org/10.1016/j.ijpx.2026.100588 (Original work published 2026)