Highly efficient, base-catalysed, intramolecular hydroamination of non-activated olefins
(2008) Tetrahedron — Vol. 64, n° 6, p. 1077-1087 (2008)
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- The intramolecular hydroamination of a large variety of non-activated alkenes can be efficiently catalysed by small amounts of lithium bases, providing smoothly and in high yields the corresponding five- and six-membered ring heterocycles. Fused and bridged bicyclic amines, of varying ring sizes, can be readily prepared either by a sequential hydroamination process or by a tandem, double addition reaction. (c) 2007 Elsevier Ltd. All rights reserved.
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Quinet, C., Jourdain, P., Hermans, C., Atest, A., Lucas, I., & Marko, I. (2008). Highly efficient, base-catalysed, intramolecular hydroamination of non-activated olefins. Tetrahedron, 64(6), 1077-1087. https://doi.org/10.1016/j.tet.2007.11.066 (Original work published 2008)