The C18-C30 fragment of amphidinol 3 has been synthesized in a convergent fashion by employing two asymmetric Sharpless dihydroxylations, a Julia-Kocienski olefination and a Wittig reaction as the key steps.
Cossy, J., Tsuchiya, T., Reymond, S., Kreuzer, T., Colobert, F., & Marko, I. (2009). Convergent Synthesis of the C18-C30 Fragment of Amphidinol 3. Synlett : accounts and rapid communications in synthetic organic chemistry, 16, 2706-2710. https://doi.org/10.1055/s-0029-1217754 (Original work published 2009)