Responsiveness of the ACTIVLIM-CP questionnaire measuring global activity performance in children with cerebral palsy.
(2018) Developmental medicine and child neurology — Vol. 60, n° 11, p. 1178-1185 (2018)
Files
Paradis_et_al_2018.pdf
Open Access - Adobe PDF
- 313.83 KB
Details
- Authors
Paradis, Julie 
Thonnard, Jean-Louis
- Abstract
- To investigate the responsiveness of the ACTIVLIM-CP questionnaire after two evidence-based interventions for children with cerebral palsy (CP). Seventy-five children with CP either participated in an intensive motor-skill learning intervention (hand-arm bimanual intensive therapy including lower extremities [HABIT-ILE], n=47) or received botulinum neurotoxin-A (BoNT-A) injection(s) into lower extremities combined with conventional physical therapy (n=28). All children were assessed three times: at baseline (T ; before HABIT-ILE/the day of BoNT-A injection), at T (last day of HABIT-ILE/6wks after BoNT-A injection), and at follow-up (T ; 3-4mo after the beginning of intervention). Parents completed ACTIVLIM-CP and three other activity questionnaires. Responsiveness was analysed using group (based on intervention), subgroup (based on gross motor function level), and individual approaches. For the HABIT-ILE group, significant improvements in ACTIVLIM-CP were observed for the T -T period (p<0.001) but not for the T -T period. No significant changes were found in the BoNT-A group during assessments (p=0.84). In the subgroup analysis for the HABIT-ILE group (T -T ), greater changes were demonstrated for children in Gross Motor Function Classification System levels III and IV (p<0.001, effect size=1.36). The individual approach was congruent with the group approach. ACTIVLIM-CP demonstrated high responsiveness after HABIT-ILE, showing that this scale may be used to investigate global activity performance in clinical trials focusing on improving daily life activities. Good responsiveness of ACTIVLIM-CP questionnaire during intensive motor-skill learning intervention. Higher responsiveness for children in Gross Motor Function Classification System (GMFCS) levels III and IV versus I and II after intensive intervention. ACTIVLIM-CP is useful to identify children improving their performance after botulinum neurotoxin-A injection.
- Affiliations
Citations
Paradis, J., Arnould, C., Thonnard, J.-L., Houx, L., Pons-Becmeur, C., Renders, A., Brochard, S., & Bleyenheuft, Y. (2018). Responsiveness of the ACTIVLIM-CP questionnaire measuring global activity performance in children with cerebral palsy. Developmental medicine and child neurology, 60(11), 1178-1185. https://doi.org/10.1111/dmcn.13927 (Original work published 2018)