Un cas inhabituel d’entéropathie secondaire à la prise d’olmesartan
(2019) Annales de Pathologie — Vol. 39, n° 3, p. 237-240 (2019)
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- (en) [An unusual case of olmesartan induced enteropathy] Olmesartan induced enteropathy was first described in 2012. It is a rare adverse effect of this antihypertensive drug. The clinical presentation commonly includes severe chronic diarrhea leading to weight loss and a variable degree of dehydration. Histological findings are most commonly observed in the duodenum and consist of partial or total villous atrophy, increased intraepithelial lymphocytes and inflammation in the lamina propria. Involvement of gastric and colic mucosa has also been described. We report on the case of a 63-year-old man, treated by olmesartan, who presented with severe chronic diarrhea. Biopsies from different levels of the gastrointestinal tract revealed a pandigestive intraepithelial lymphocytosis.
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Henry, P., Dano, H., Piessevaux, H., & Mourin, A. (2019). Un cas inhabituel d’entéropathie secondaire à la prise d’olmesartan. Annales de Pathologie, 39(3), 237-240. https://doi.org/10.1016/j.annpat.2018.10.007 (Original work published 2019)